evaluation of neuroimaging in cerebral palsy
نویسندگان
چکیده
objective cerebral palsy (cp), a common static motor neurological disorder of childhood with wide spectrum of underlying etiologies, can be demonstrated with different neuro imaging techniques. we undertook this study to investigate the diagnosis of intracranial lesions in children with cp and its correlation between clinical deficits and neuroradiological findings. materials and methods in this prospective hospital-based study, the data of 120 patients with cp, aged below 18 years, referring to the neurology clinic of the ali asghar pediatric hospital in tehran was studied; data on their cranial neuroimaging findings was analyzed any possible association(s) between the gestational ages, prenatal history and neurological deficits were investigated. results of the 120 patients, 72 (60%) were male; 75% were aged below 7 years. common predisposing factors were prenatal asphyxia, lbw, prematurity and toxemia of pregnancy. of the 120 cases, 90%(107) had spastic cp, with the quadriplegic type being the most common (54%), followed by spastic paraplegia (21%); twenty-four patients (20%) had significant preventricular leucomalacia (pvl), a finding more common among those born pre-term. sixteen patients had hemiplegic cp, 14 of whom showed unilateral lesions on brain mri imaging. ten (8%) had extra pyramidal cp, a condition more common among term born infants, while six of the 10(72%) showed significant abnormalities on the basal ganglia. cerebral atrophy was seen in 60 (50%) of patients and pvl in 20%; encephalomalacia, gliosis, middle cerebral artery infarcts, pvl and gliosis indicated hypoxia as a risk factor for cp. extent of mri lesions correlated with the severity of neurological deficits in cp lesions, which were more extensive in quadriplegics and double hemiplegics rather than paraplegics, and among those delivered preterm as compared to those born at term. conclusion radiological findings were found to be closely related to the type of cp and the neurological deficits and gestational ages of patients with brain insult; we believe that mri is helpful in delineating the underlying etiology, extent, severity and timing of insult to the developing brain and prognostication in cp patients.
منابع مشابه
neuroimaging in cerebral palsy – report from north india
how to cite this article: aggarwal a, mittal h, debnath skr, rai a. neuroimaging in cerebral palsy–report from north india. iran j child neurol. 2013 autumn; 7(3):41- 46. objective only few indian reports exist on neuroimaging abnormalities in children with cerebral palsy (cp) from india. materials & methods we studied the clinico-radiological profile of 98 children diagnosed as cp at a ter...
متن کاملNeuroimaging in Cerebral Palsy – Report from North India
OBJECTIVE Only few Indian reports exist on neuroimaging abnormalities in children with cerebral palsy (CP) from India. MATERIALS & METHODS We studied the clinico-radiological profile of 98 children diagnosed as CP at a tertiary centre in North India. Relevant investigations were carried out to determine the etiology. RESULTS Among the 98 children studied, 80.5% were males and 22.2% were pre...
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The American Academy of Neurology now recommends that all cases of cerebral palsy of unknown origin undergo neuroimaging. Controversy surrounds this recommendation because of concerns about the adequacy of the supporting evidence. This article reviews the evidence provided by magnetic resonance imaging (MRI) and computed tomography (CT) imaging studies in cerebral palsy and discusses the potent...
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عنوان ژورنال:
iranian journal of child neurologyجلد ۲، شماره ۲، صفحات ۳۳-۳۸
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